Sciatica is a painful syndrome caused by compression or irritation of the sciatic nerve. The sciatic nerve runs deep through the buttock and down the leg. Sciatica can range from a dull ache to an incapacitating pain. Symptoms may be constant or intermittent, depending on activities or time of day. Osteopathy can be useful in relieving the symptoms of sciatica. Osteopaths will usually conduct a full musculoskeletal and orthopaedic examination to find the true underlying cause of the sciatica. Osteopaths treat the related joints, muscles, ligaments or tendons to reduce the pressure on the sciatic nerve. Sciatica can often resolve quickly with the appropriate management and self-care.